Phosphate of Zirconium as a Reusable Efficient Catalyst for the Synthesis of 2-Arylquinazolin-4(3H)-ones

Abstract

Our work is around the heterogeneous catalysts based on phosphate. This is all the more important as Morocco has a significant wealth of world reserves of this mineral. This application of natural phosphate alone or modified, has been successfully generalized to many reactions (Claisen Schmidt condensation, selective hydration of nitriles…). And more precisely, the zirconium phosphate catalyst, its physicochemical parameters and catalytic application in the synthesis of 2-arylquinazolin-4(3H)-ones have been studied in order to opt for the one that offers the most economic, ecological and technical advantages.