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article · Bioinformatics Advances

Pharmacological assessment of <i>Coffea arabica</i> compounds as potential therapeutics for cervical cancer

20243 citationsOpen accessUniversity of Ibadan

Abstract

The data supporting the findings of this study, including bulk RNA-seq gene expression data, survival, and phenotype data, are available through the TCGA database. These data can be accessed via the Xenabrowser platform (https://xenabrowser.net) using the reference identifier [TCGA Cervical Cancer (CESC)]. Corresponding healthy cervical tissue RNA-seq data, are available through the Genotype-Tissue Expression (GTEx) project (https://www.gtexportal.org/home/). The codes used for differential gene expression (DGE) analysis, pathway enrichment, and survival analysis, as well as scripts for generating volcano plots (DGE analysis), Kaplan-Meier survival plots, and boxplots (gene expression), and machine learning implementations are available on GitHub (https://github.com/Ponaskillzyy/Coffea_arabica_Potential_in_Cervical_Cancer).

Research topics

  • Antioxidant Activity and Oxidative Stress
  • Genomics, phytochemicals, and oxidative stress
  • Protein Hydrolysis and Bioactive Peptides

Sustainable Development Goals

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DOI: 10.1093/bioadv/vbaf132

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