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article · Clinical Microbiology and Infection

Performance of diagnostic procedures for bubonic plague in endemic settings in Madagascar: a prospective test accuracy sub-study within the IMASOY trial

Abstract

PCR outperforms culture, the previous reference standard. While serology adds diagnostic value, it is impractical for routine use. The F1RDT done on site cannot be relied upon for clinical case management decisions. F1RDT performs better under laboratory conditions and could be implemented in peripheral laboratories for surveillance purposes in resource-constraint settings.

Research topics

  • Yersinia bacterium, plague, ectoparasites research
  • Toxoplasma gondii Research Studies
  • Vector-borne infectious diseases

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DOI: 10.1016/j.cmi.2025.12.002

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