Pain Assessment among Egyptian Children with Transfusion-Dependent Hemoglobinopathies: Pilot Study

Abstract

Background: Hemoglobinopathies that require transfusions are among the most prevalent hereditary disorders in theworld. Transfusion-dependent hemoglobinopathies cause unpredictable, recurrent, and frequently permanent pain,making them distinct from other pain syndromes. Objective: - This paper aims to evaluate the experience of pain inchildren diagnosed with transfusion dependent hemoglobinopathies. Additionally, it seeks to explore the associationsbetween pain and various sociodemographic and clinical factors in the sample of children under study. Methodology:This cross-sectional, descriptive study comprised a sample of children between the ages of 8 and 18 years who hadtransfusion-dependent hemoglobinopathies. The data was obtained from the hematology clinic located at Children'sHospital, affiliated with Mansoura University in Egypt. The data was collected by the utilization of a semi-structuredinterview form and the implementation of the revised-Face, Leg, Activity, Cry, and Consolability scale (r-FLACC).Results: Of the children who participated in the research, two-thirds (66%) were female, and 76% had been diagnosedwith beta-thalassemia. Of the children who participated in the study, over half (56%) experienced significant painsymptoms. Children with sickle cell disease who undergo twice-monthly blood transfusions and have been studied reportexperiencing severe pain. Conclusion: Of the children who participated in the study, over half experienced severe painsymptoms. Types of transfusion-dependent hemoglobinopathies, particularly sickle cell disease, and twice-monthlyblood transfusions, have been linked with severe pain levels. Recommendations: - Regular evaluations and improvedpain management programs aimed at pain reduction, would significantly enhance the well-being of pediatric patientsdiagnosed with transfusion-dependent hemoglobinopathies.