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article · Journal of Crohn s and Colitis

P182 Hepatic lesions in chronic inflammatory bowel disease revealed by liver biopsy during surgery

2024Open accessMohamed I University

Abstract

Abstract Background Chronic inflammatory bowel diseases are complicated in 10 to 30% cases by hepatobiliary abnormalities, the aim of this study was to evaluate the prevalence of histological liver abnormalities and demonstrate the advantages of performing a systematic liver biopsy during surgery. Methods from 2018 to 2022,twenty patients underwent surgery for inflammatory bowel disease (IBD) with systematically liver biopsy during the procedure . Results Twenty IBD patients were operated (sex ratio M / F: 1.5),the mean age was 31.7 years, during a mean follow-up of three years before surgery ; occlusive syndrome was the dominated indication of surgery in 90% cases, and acute colitis in 10% cases,two patients had cytolysis,and one patient had cholestasis,four patients had radiologically steatosis.Histologically,fourteen patients had small duct cholangitis (chronic or subacute portitis, portal fibrosis),five patients had steatosis and one patient presented with primary sclerosing cholangitis . Conclusion peroperative liver biopsy identify liver diseases in an early diagnosis and as a result medical treatment was adapted and regular surveillance of the liver was ensured.

Research topics

  • Inflammatory Bowel Disease
  • Liver Diseases and Immunity
  • Gallbladder and Bile Duct Disorders

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DOI: 10.1093/ecco-jcc/jjad212.0312

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