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article · BMC Pulmonary Medicine

Outcomes of biological therapy in patients with severe asthma with chronic rhinosinusitis in Saudi Arabia: patients with nasal polyps versus those without nasal polyps

20243 citationsOpen accessBeni Suef University

Abstract

Patients with CRS experienced significant improvements in clinical, FEV1, and laboratory outcomes after dupilumab therapy. However, these improvements were not maintained when comparing CRSwNP with CRSsNP. There were no significant differences between those with and without NP regarding ACT and OCs use or laboratory (eosinophilic count, serum IgE level) parameters. Further prospective multicenter studies are warranted.

Research topics

  • Sinusitis and nasal conditions
  • Allergic Rhinitis and Sensitization
  • Asthma and respiratory diseases

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DOI: 10.1186/s12890-024-03139-x

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