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article · Current Pharmaceutical Biotechnology

Optimization of Phloretin-loaded Nanospanlastics for Targeting of FAS/SREBP1c/AMPK/ OB-Rb Signaling Pathway in HFD-induced Obesity

20245 citationsBeni Suef University

Abstract

Administration of PTN-NSLs significantly attenuated the levels of glycemic, oxidative stress, and inflammatory biomarkers. The biochemical and PCR findings are aided by histological investigations. Also, the present findings imply that PTN-NSLs might be a promising pharmacological tool for the treatment of obesity-related diseases.

Research topics

  • Phytochemicals and Antioxidant Activities
  • Tea Polyphenols and Effects
  • Adipokines, Inflammation, and Metabolic Diseases

Sustainable Development Goals

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DOI: 10.2174/0113892010278684240105115516

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