Optic nerve sheath meningioma detected by somatostatin receptor scintigraphy with [99mTc]Tc-Tektrotyd

Abstract

Optic nerve sheath meningiomas are rare and difficult to diagnose accurately due to the high risk of visual loss associated with histologic confirmation. Currently, the primary imaging techniques used for diagnosis are contrast-enhanced computed tomography (CT) and magnetic resonance imaging (MRI). However, these methods may not always provide a definitive diagnosis, necessitating alternative approaches. This case study is one of the few that reports the use of a [99mTc]Tc-Tektrotyd single-photon emission computed tomography (SPECT/CT) scan for the non-invasive diagnosis of an orbital space-occupying tumor. This radiopharmaceutical can bind with high affinity to somatostatin receptor subtype 2, which is expressed in meningiomas.