article · Materials Advances

Novel chitosan hybrid fluorinated thiourea derivatives as dual anti-microbial and anti-biofilm agents: tailoring molecular interactions, <i>in silico</i> toxicity, and docking simulation

Moustafa S. Abusaif
Nabila A. Maziad
Mohamed A. Salem
Ahmed Ragab
Yousry A. Ammar

2026Open accessSuez University

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Abstract

This article presents the synthesis of chitosan isothiocyanate, followed by hybridization with promising fluorinated aromatic amines, producing three chitosan fluorinated-thiourea samples (CHTUD1–3).

Research topics

Antimicrobial agents and applications
Fluorine in Organic Chemistry
Bacterial biofilms and quorum sensing

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DOI: 10.1039/d6ma00145a

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