Neuromeningeal cryptococcosis (CNM) in an immunocompromised child

Abstract

Background: Cryptococcal meningitis is one of the most common opportunistic infections in immunocompromised patients. Mostly it manifests as subacute/chronic meningitis, although pathological findings suggest extensive tissue invasion of the brain parenchyma and meninges. This disease has a very high mortality rate, even with the administration of an antifungal combination.