article · Children
More than half of the participants were boys, with an average age of 4 years. Remarkably, 95.8% (score T < x¯ +2 SD) of children scored below average on the Mullen Scales. Significant associations were found between early neurocognitive development and factors like maternal depression, socioeconomic status, maternal education, age of weaning, and responses to the Ten-Questions Questionnaire (<i>p</i> < 0.005). Conclusion, children with sickle cell disease show below-average cognitive development, with maternal depression being a critical factor. Longitudinal studies are vital to understanding the long-term cognitive effects of sickle cell disease, particularly in the Democratic Republic of Congo, where targeted support is urgently needed.
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DOI: 10.3390/children11121521
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