article · Journal of research in pharmaceutical science.
Conventional cancer therapies such as chemotherapy and radiotherapy have supported patients for many years, but their adverse side effects limit their effectiveness. Consequently, scientific attention is shifting towards natural products derived from medicinal plants to discover innovative anticancer agents. This work reviews the diversity of Nigerian medicinal plants, detailing their traditional applications alongside their assessed anticancer activities. It outlines scientific research trends, focusing on laboratory in vitro and in vivo studies conducted to evaluate the antitumour effects of these plant-derived compounds. In addition, it examines the biological mechanisms of action and highlights the potential benefits natural substances offer over standard treatments. Finally, investigative methods are outlined to support more effective future research into plant-based cancer therapies.
Cancer remains a leading cause of death worldwide, and standard treatments often trigger severe side effects. Exploring the chemical richness of Nigerian medicinal plants can uncover safer, targeted treatments. Understanding their biological mechanisms and traditional applications helps researchers validate natural compounds, guiding the development of more tolerable and effective future therapies.
The findings outline potential starting points for oncology drug developers and pharmaceutical researchers seeking natural anticancer leads. By reviewing active Nigerian flora, the work aids early-stage compound screening. However, because the evidence is bounded by early in vitro and in vivo laboratory studies alongside traditional use documentation, the technology sits at an early discovery stage, far from clinical deployment or commercial product formulation.
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Cancer is one of the leading causes of global death. For ages, research has been carried out to find a lasting cure to this global burden. Conventional cancer treatment such as Chemotherapy, Radiotherapy had been helpful over the years. But this treatment has its adverse side effect which makes it not an effective tool in cancer treatment. Of recent, Scientists have shifted their focus to Natural Products from Medicinal Plants. Natural products are integral to the development of innovative anticancer drugs in cancer research, offering the scientific community the possibility of exploring novel natural compounds against cancers. This study focuses on the diversity of Nigeria plants; its traditional uses and also its anticancer activities. This study also focuses on scientific studies and research trends on Nigeria Medicinal plants, In Vivo and In vitro studies conducted on the plants to assess their antitumor activities. The study also shows the mechanism of action and potential benefits of natural products over conventional cancer treatment. And also highlights investigative methods for further and effective research on cancer treatment.
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DOI: 10.35629/2995-11030124
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