article · Journal of Molecular Structure

Multitarget anti-inflammatory celecoxib-based hybrids: Design, synthesis, and mechanistic evaluation of COX-2/5-LOX/sEH modulation with liposomal formulation, ADMET profiling, and molecular dynamics studies

Osama M. Soltan
Abdelrahman Hamdi
Atsushi Narumi
Mohamed Hegazy
Shoichiro Asayama
Motoki Ueda
Abdelsalam Mohamed Abdelsalam Ouf
Hiroyuki Konno
Mohammed M. Amin
Ahmed A. El-Rashedy
Mahmoud S. Abdelbaset
Mohamed S. Elafify
Kamal S. Abdelrahman
Amr K.A. Bass

2026Al-Azhar University

In plain language

No abstract is available for this record, so no summary has been generated.

Research topics

Eicosanoids and Hypertension Pharmacology
Inflammatory mediators and NSAID effects
Antiplatelet Therapy and Cardiovascular Diseases

Read the original research

This page summarises published work. The authoritative version sits with the publisher.

View on publisher site Record on OpenAlex

DOI: 10.1016/j.molstruc.2026.147215

Is something wrong with this record? Report it or request removal.

Discussion

Discuss this research

Have you built on this work, tried to replicate it, or seen it applied in practice? Share what you know. Verified researchers and MARATTO™ domain experts can open a discussion, and any member can reply. Contributions are reviewed before they appear.

No discussion yet. Open the first thread.

New to MARATTO™? Create a free account.