article · Microbiology Spectrum

Mucosal tenofovir 1% gel stimulates cell proliferation and type I/III interferon pathways

Sean M. Hughes
Jim Pickett
Kenzie Birse
Rhonda M. Brand
Gonasagrie Nair
Ross Cranston
James Y. Dai
Adam Burgener
Bhavna Balar
Alicia R. Berard
Cheryl Cameron
Kim A. Woodrow
Germán G. Gornalusse
Claire Levy
Craig W. Hendrix
Fernanda L. Calienes
Javier R. Lama
Mark J. Cameron
Jessica Justman
Joanne D. Stekler
Romel D. Mackelprang
Urvashi Pandey
Kenneth H. Mayer
Ian McGowan
Laura Noel-Romas
Mark A. Marzinke
Florian Hladik

2026Open accessStellenbosch University

In plain language

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Abstract

This study is registered with ClinicalTrials.gov as NCT01768962, NCT01687218, and NCT01232803.

Research topics

Virus-based gene therapy research
Cytomegalovirus and herpesvirus research
interferon and immune responses

Sustainable Development Goals

Zero Hunger

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DOI: 10.1128/spectrum.01680-25

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