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article · Open Forum Infectious Diseases

Monthly Sulfadoxine-Pyrimethamine During Pregnancy Prevents Febrile Respiratory Illnesses: A Secondary Analysis of a Malaria Chemoprevention Trial in Uganda

202410 citationsOpen accessMakerere University

Abstract

Monthly IPTp-SP was associated with reduced respiratory NMFI incidence, revealing a potential nonmalarial mechanism of SP and supporting current World Health Organization recommendations for IPTp-SP, even in areas with high-grade SP resistance. While maternal respiratory NMFIs are known risk factors of lower birthweight, most women in our study were presumptively treated with antibiotics, masking the potential benefit of SP on birthweight mediated through preventing respiratory NMFIs.

Research topics

  • Malaria Research and Control
  • Pregnancy and preeclampsia studies
  • Pregnancy and Medication Impact

Sustainable Development Goals

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DOI: 10.1093/ofid/ofae143

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