article · Open Forum Infectious Diseases

Molecular Surveillance of Malaria in Nigeria Reveals a Low Frequency of Antimalarial Resistance Markers and Clonal Expansion of Chloroquine-Sensitive Infections

Olusola Ajibaye
Nuredin Mohammed
Eniyou Oriero
Ifeoma Idigbe
Mary Aigbiremo Oboh-Imafidon
CO Falade
Umberto D’Alessandro
Olumide Ajibola
Mouhamadou Fadel Diop
F Patience Olusola
Brandon Nji Amambua-Ngwa
Chinedu Ogbonnia Egwu
Martin Meremikwu
Amambua-Ngwa Alfred

2025Open accessUniversity of Ibadan

Abstract

Chloroquine sensitivity at the molecular level is now dominant in Nigeria, while antifolate resistance persists. Enhanced molecular surveillance of drug resistance-associated loci will serve as an early warning to safeguard the efficacy of chemointerventions in Nigeria.

Research topics

Malaria Research and Control
Pharmaceutical Quality and Counterfeiting
Parasitic Diseases Research and Treatment

Sustainable Development Goals

Good Health and Well-being

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DOI: 10.1093/ofid/ofaf719

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