article · Frontiers in Microbiology

Metagenomic insights into the urban–rural variation of antimicrobial resistance and pathogen reservoirs in untreated wastewater from central India

Bailey Secker
Edward Acheampong
Amit R. Nayak
Aditi Nag
Rachel L. Gomes
Sandeep Shrivastava
Aliabbas A. Husain
Adam Blanchard
Rajpal S. Kashyap
Robert J. Atterbury
Vishwanath Prashant
Umashankar Vetrivel
Sudipti Arora
Tarun Bhatnagar
Andrew C. Singer
Tanya Monaghan

2026Open accessUniversity of Ghana

Abstract

These findings show that wastewater metagenomics sensitively resolved clinically relevant pathogens and ARGs in an Indian urban-rural setting, capturing nuanced geographic structure. Integrating routine DNA metagenomics into One Health environmental surveillance could strengthen AMR early warning and guide interventions in resource-constrained contexts.

Research topics

Pharmaceutical and Antibiotic Environmental Impacts
Antibiotic Resistance in Bacteria
Fecal contamination and water quality

Sustainable Development Goals

Clean Water and Sanitation

Read the original research

This page summarises published work. The authoritative version sits with the publisher.

View on publisher site Record on OpenAlex

DOI: 10.3389/fmicb.2025.1722229

Is something wrong with this record? Report it or request removal.

Discussion

Discuss this research

Have you built on this work, tried to replicate it, or seen it applied in practice? Share what you know. Verified researchers and MARATTO™ domain experts can open a discussion, and any member can reply. Contributions are reviewed before they appear.

No discussion yet. Open the first thread.

New to MARATTO™? Create a free account.