article · Cureus

Melatonin Mitigates Cisplatin-Induced Submandibular Gland Damage by Inhibiting Oxidative Stress, Inflammation, Apoptosis, and Fibrosis

Alaa M. Badawy
Ahmed El-Metwally
Ibrahim El-Shenbaby
Medhat Taha
Noha Hammad Sakr
Azza I. Helal
Tourki A. S. Baokbah
Emadeldeen Hussin
Sara Abubakr
Mohie Mahmoud Ibrahim
Amira E. Farage

20242 citationsOpen accessKafr el-Sheikh University

Abstract

Melatonin attenuated cisplatin-induced submandibular destruction alleviating SMG oxidative stress, inflammation, and fibrosis in addition to halting cellular apoptosis, sheds light on its usage in clinical application.

Research topics

Chemotherapy-induced organ toxicity mitigation
Effects of Radiation Exposure
Phytoestrogen effects and research

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DOI: 10.7759/cureus.68515

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