review · Nutrients
Very few studies have been designed specifically to evaluate how herbal preparations influence targets or pathways related to the microbiota-gut-brain axis. Nonetheless, the wider literature provides multiple indications of potential interactions with this system. Observed effects include an increased abundance of health-promoting microorganisms, anti-inflammatory responses, and pathway modulation driven by gut microbial metabolites. In particular, recorded data for Panax ginseng, Schisandra chinensis, and Salvia rosmarinus indicate that interactions between their constituent compounds and the gut microbiota could mediate mental health benefits. Despite these positive indicators, dedicated investigations directly examining effects on pathways associated with the microbiota-gut-brain axis remain necessary for the majority of medicinal plants.
Understanding the links between herbal remedies, the gut microbiome, and mental health could support the development of nature-based therapeutic strategies. By highlighting how plants such as ginseng and rosemary might influence mental wellbeing through gut pathways, this synthesis helps clarify current scientific understanding while identifying where further targeted research is required.
The abstract points towards potential therapeutic or nutraceutical applications using specific plants, such as Panax ginseng, Schisandra chinensis, and Salvia rosmarinus, for mental health support. However, this work remains at an early stage of research. Product developers and clinical researchers would need dedicated studies on biological pathways before these herbal preparations can be validated for commercial formulations or clinical use.
AI-generated from the published abstract. Always read the original work before citing.
Only a few studies have been specifically designed to assess how herbal preparations affect MGBA-related targets or pathways. However, many studies provide hints of a possible interaction with the MGBA, such as an increased abundance of health-beneficial microorganisms, anti-inflammatory effects, or MGBA-related pathway effects by gut microbial metabolites. Data for <i>Panax ginseng</i>, <i>Schisandra chinensis</i>, and <i>Salvia rosmarinus</i> indicate that the interaction of their constituents with the gut microbiota could mediate mental health benefits. Studies specifically assessing the effects on MGBA-related pathways are still required for most medicinal plants.
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DOI: 10.3390/nu14102111
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