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article · Wellcome Open Research

Maternal and child immune profiles are associated with neurometabolite measures of early-life neuroinflammation in children who are HIV-exposed and uninfected: a South African birth cohort

Abstract

In this South African cohort, HIV exposure-specific associations were observed between certain mother and child immune markers and child neurometabolite ratios at 2-3 years. Larger, longitudinal neuroimaging studies integrating neurodevelopmental outcomes are needed to clarify mechanisms and clinical implications.

Research topics

  • HIV Research and Treatment
  • Tryptophan and brain disorders
  • Neonatal and fetal brain pathology

Sustainable Development Goals

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DOI: 10.12688/wellcomeopenres.24911.2

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