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article · Frontiers in Urology

Low yield of pathological lymph node metastasis among patients with invasive penile squamous cell carcinoma in the context of high HIV burden: evidence from a prospective cohort study in Zambia

2026Open accessUniversity of Zambia

Abstract

The study demonstrates a modestly low yield of pathological inguinal lymph node metastasis in patients with clinically palpable nodes in the context of a high HIV burden. Minimally invasive biopsy techniques to assess nodal status should be explored in this setting to reduce the morbidity associated with surgical staging while accurately assessing nodal status.

Research topics

  • Genital Health and Disease
  • Female Genital Mutilation/Cutting Issues
  • Cervical Cancer and HPV Research

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DOI: 10.3389/fruro.2026.1727689

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