preprint

Low systemic IFN response and high viral load are associated with COVID-19 disease severity in unvaccinated patients in Kenya, 2022-2023

Rebeccah M. Ayako
Simeon Mining
Kirtika Patel
Jonas Klingström
Isaac Ndede
Johan Nordgren
Marie Larsson

2025Open accessMoi University

Abstract

Cellular and humoral responses, as well as virus replication kinetics, may affect the severity of COVID-19. This study examined systemic and mucosal immune responses as well as viral load in unvaccinated SARS-CoV-2 patients. Forty-eight COVID-19-posit

Research topics

SARS-CoV-2 and COVID-19 Research
Immune responses and vaccinations
COVID-19 Clinical Research Studies

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DOI: 10.22541/au.174768064.40021112/v1

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