article · Open Forum Infectious Diseases

Low Prevalence of Nirmatrelvir-Ritonavir Resistance-Associated Mutations in SARS-CoV-2 Lineages From Botswana

Wonderful T. Choga
Simani Gaseitsiwe
Dorcas Maruapula
Mosepele Mosepele
Irene Gobe
Roger Shapiro
Shahin Lockman
Jonathan Z. Li
Natasha O. Moraka
Patience Motshosi
Boitumelo Zuze
Ontlametse T. Bareng
Joseph Makhema
Tendani Gaolathe
Kedumetse Seru
Nokuthula S Ndlovu
Trevor J. Tamura
Mogomotsi Matshaba
Teko Matsuru
Matshwenyego Boitswarelo
Sikhulile Moyo

20242 citationsOpen accessBotswana International University of Science and Technology

Abstract

The frequency of NTV/r RAMs in Botswana was low. Higher rates were observed in Delta VOCs compared to Omicron and Beta VOCs. As NTV/r use expands globally, continuous surveillance for drug-resistant variants is essential, given the RAMs identified in our study.

Research topics

SARS-CoV-2 and COVID-19 Research
COVID-19 Clinical Research Studies
SARS-CoV-2 detection and testing

Sustainable Development Goals

3Good Health and Well-being

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DOI: 10.1093/ofid/ofae344

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