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article · Frontiers in Microbiology

Low prevalence of archived integrase strand transfer inhibitors resistance associated mutations in Botswana before the roll out of dolutegravir based first line antiretroviral therapy

20242 citationsOpen accessUniversity of Botswana

Abstract

The overall prevalence of archived INSTI RAMs in Botswana was low prior to transitioning to first-line DTG-based ART regimens, and did not differ between ART-naïve and ART-experienced individuals. Ongoing surveillance of INSTI DRMs in Botswana will allow for re-assessment of INSTI resistance risk following nationwide DTG rollout.

Research topics

  • HIV/AIDS drug development and treatment
  • HIV/AIDS Research and Interventions
  • HIV Research and Treatment

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DOI: 10.3389/fmicb.2024.1482348

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