article · JAIDS Journal of Acquired Immune Deficiency Syndromes

Longitudinal Changes in Tenofovir and Tenofovir Diphosphate Concentrations Among Pregnant Women Using Oral PrEP for HIV Prevention: Findings From Durban, South Africa

Ivana Beesham
Christina Psaros
Craig W. Hendrix
Yolandie Kriel
Jessica E. Haberer
Jiaying Hao
David R. Bangsberg
Jennifer Smit
Manjeetha Jaggernath
Patricia M. Smith
Lynn T. Matthews

20242 citationsUniversity of the Witwatersrand

Abstract

PrEP use declined during pregnancy by all measures. Discrepancies between pillcap measurements and drug concentrations could be due to physiologic changes during pregnancy or under- or overuse of the pillcaps. Determining what drug metabolite concentrations are needed to confer protection during pregnancy is important for optimizing counseling and prevention support.

Research topics

HIV/AIDS Research and Interventions
HIV-related health complications and treatments
HIV, Drug Use, Sexual Risk

Sustainable Development Goals

3Good Health and Well-being

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DOI: 10.1097/qai.0000000000003586

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