article · Journal of Antimicrobial Chemotherapy

Lamivudine dosing for preterm infants exposed to HIV: a population pharmacokinetic modelling and simulation study

Adrie Bekker
Martina Penazzato
Mark F. Cotton
Avy Violari
Diana F. Clarke
Roger Shapiro
Kulkanya Chokephaibulkit
Edmund V. Capparelli
Elaine J. Abrams
Katie McCarthy
Jack Moye
Mark Mirochnick
Theodore Ruel
Tim R. Cressey

20241 citationOpen accessUniversity of the Witwatersrand

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Abstract

Model-based predictions support twice daily pragmatic GA band dosing of lamivudine for preterm infants, but clinical validation is warranted.

Research topics

Pharmaceutical studies and practices
HIV/AIDS drug development and treatment
Pharmacological Effects and Toxicity Studies

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DOI: 10.1093/jac/dkae259

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