Integrated metabolomic, nanoformulation, and network pharmacology approach reveals multifunctional bioactivities of an Ocimum sanctum nanoemulsion

Abstract

Collectively, this metabolomics-guided O. sanctum nanoemulsion represents a promising plant-derived nanosystem. This preliminary study demonstrates its potential anticancer, antibacterial, antioxidant, and anti-inflammatory activities in vitro. However, further detailed investigations, including more extensive in vitro studies as well as in vivo evaluations, are required to better elucidate its mechanisms, safety, and potential biological applications.