Identification of Compounds in the Ethyl Acetate Fraction of Hyptis suaveolens Leaves by HPLC-ESI- Q-TOF -MS/ MS Analysis

Abstract

Hyptis suaveolens is a plant of Ivory Coast flora. Preliminary studies have shown that the plant's leaves possess multiple medicinal properties, certainly due to the presence of terpenic and phenolic compounds. Yet, the plant's leaves compounds structures have been fewest elucidated. This study aim to determine the structures of a number of known compounds present in the ethyl acetate fraction obtained from the hydroethanol extract of Hyptis suaveolens leaves. Thus, fifteen known compounds structures were identified in ethyl acetate fraction of the plant's leaves by dereplication method. Nine of these compounds, are phenolic compounds and the others are terpenoids. Five of these compounds had not yet been elucidated in the leaves of Hyptis suaveolens. All these bioactive molecules in Hyptis suaveolens leaves makes this plant an alternative for combating many diseases caused by oxidative stress.