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article · Current Computer - Aided Drug Design

<i>In silico</i> Exploration of a Novel ICMT Inhibitor with More Solubility than Cysmethynil against Membrane Localization of KRAS Mutant in Colorectal Cancer

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Abstract

According to the results obtained, the identified compound presented a high solubility in water and could be similar to the pharmacological activity of cysmethynil.

Research topics

  • Computational Drug Discovery Methods
  • Pharmacogenetics and Drug Metabolism
  • Cancer, Hypoxia, and Metabolism

Sustainable Development Goals

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DOI: 10.2174/0115734099264451231003172217

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