article · Toxicology Mechanisms and Methods

<i>In silico and in vivo</i> toxicity assessment of cysteamine-modified nanoparticles: implications for pharmacotherapy application

Babatunde Alabi
Fisayo Nathaniel Ogunleye
Sodiq Kolawole Lawal
Samuel Oluwaseun Olojede
Diana Odey Ochuole
Olamide Adesanya
Amina Suleiman
Benneth Ben‐Azu

2025Osun State University

Abstract

BACKGROUND: Given the increasing therapeutic potential of cysteamine (CYST) at appropriate doses and expert concerns regarding the toxicity of nanoparticles, this study aimed to assess the toxicity profile of both CYST and silver nanoparticles conjugated with cysteamine (CYST-AgNPs). METHODS: cardiac puncture and processed according to the standard hematological analysis protocols. RESULTS: < 0.05). CONCLUSION: safety analysis and pharmacological potential of cysteamine-modified silver nanoparticles (CYST-AgNPs), suggesting enhanced therapeutic activity.

Research topics

Biomedical Research and Pathophysiology
Saffron Plant Research Studies
Neonatal Health and Biochemistry

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DOI: 10.1080/15376516.2025.2538128

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