article · Journal of Pharmacy and Pharmacology

<i>Delonix regia</i> flower extract protects against diabetic cardiac remodeling via modulating eNOS/NO/cGMP and NF-κB/iNOS/TNF-α trajectories

2026Zagazig University

Abstract

Methanolic extract of D. regia may have therapeutic potential in the attenuating left ventricular remodeling associated with diabetic cardiomyopathy. These effects appear to be associated with modulation of eNOS/NO/cGMP and NF-κB/iNOS/TNF-α trajectories, along with anti-apoptotic and antifibrotic actions.

Research topics

Cardiovascular Function and Risk Factors
Cardiac Fibrosis and Remodeling
Cardiac Ischemia and Reperfusion

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DOI: 10.1093/jpp/rgag024

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