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article · New England Journal of Medicine

<i>APOL1</i> Bi- and Monoallelic Variants and Chronic Kidney Disease in West Africans

202460 citationsOpen accessUniversity of Ibadan

In plain language

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Abstract

In this study, monoallelic <i>APOL1</i> variants were associated with 18% higher odds of CKD and 61% higher odds of focal segmental glomerulosclerosis; biallelic <i>APOL1</i> variants were associated with 25% higher odds of CKD and 84% higher odds of focal segmental glomerulosclerosis. (Funded by the National Human Genome Research Institute and others.).

Research topics

  • Renal Diseases and Glomerulopathies
  • Celiac Disease Research and Management
  • Chronic Lymphocytic Leukemia Research

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DOI: 10.1056/nejmoa2404211

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