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article · JAMA Otolaryngology–Head & Neck Surgery

Hypotensive Agents for Controlled Hypotension in Endoscopic Sinus Surgery

2026Open accessAl-Azhar University

Abstract

In this systematic review and network meta-analysis, controlled hypotension improved surgical field quality in ESS with comparable safety. Diltiazem, esmolol, dexmedetomidine, labetalol, and clonidine were effective; dexmedetomidine was associated with reduced MAP the most, and esmolol favored recovery.

Research topics

  • Anesthesia and Sedative Agents
  • Sinusitis and nasal conditions
  • Nausea and vomiting management

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DOI: 10.1001/jamaoto.2025.5222

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