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article · RSC Advances

Hydrothermal synthesis of Ag@Zn-salen MOF nanocomposite <i>via</i> a two-step method for ultrasensitive CA15-3 biosensing in breast cancer diagnostics

20251 citationOpen accessBritish University in Egypt

Abstract

= 20), outperforming conventional immunoassays. Stability studies confirmed less than 5% signal drift over 2 months, enabled by sodium azide preservation. This work addresses long-standing synthesis challenges in bimetallic metal-organic frameworks (MOFs), providing a scalable platform for ultrasensitive biomarker detection. The Ag@Zn-Salen MOF biosensor's precision, robustness, and clinical validity position it as a transformative tool for breast cancer monitoring and early diagnosis.

Research topics

  • Advanced Nanomaterials in Catalysis
  • Metal-Organic Frameworks: Synthesis and Applications
  • Advanced biosensing and bioanalysis techniques

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DOI: 10.1039/d5ra04548g

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