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article · bioRxiv (Cold Spring Harbor Laboratory)

Homozygosity for rare or common hypomorphic <i>IL23R</i> variants confers a predisposition to tuberculosis in humans

2026Open accessMohammed V University

In plain language

The abstract on record is too brief for a reliable plain-language summary, so none has been generated.

Abstract

Homozygous hypomorphic <i>IL23R</i> variants impair IL-23-dependent IFN-γ production and underlie tuberculosis.

Research topics

  • Psoriasis: Treatment and Pathogenesis
  • Immunodeficiency and Autoimmune Disorders
  • Dermatology and Skin Diseases

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DOI: 10.64898/2026.03.23.713554

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