book chapter · Apple Academic Press eBooks
Green synthesis offers an environmentally friendly, cost-effective, and rapid method for producing metallic nanoparticles under benign conditions. Using natural biomolecules as simultaneous reducing and capping agents eliminates hazardous chemicals, which enhances biocompatibility and ensures lower toxicity. Silver, gold, and bimetallic silver-gold alloy nanoparticles have attracted substantial interest because of their distinctive optical, physical, chemical, photothermal, catalytic, and electrical properties. These nanoparticles demonstrate significant functional utility across multiple biomedical areas, serving as antimicrobial, larvicidal, antioxidant, anticoagulant, and thrombolytic agents. Consequently, these materials provide potential avenues to address major health challenges, including rising antimicrobial resistance, vector-borne diseases, oxidative cell damage from free radical species, and blood coagulation disorders. Their combined biological and physicochemical characteristics position them as versatile tools for the development of future nanomedical interventions.
Traditional chemical synthesis of nanomaterials often relies on toxic agents and energy-intensive processes. Biological synthesis provides a benign, affordable alternative that yields highly biocompatible nanoparticles. These materials offer practical solutions for pressing global health problems, including drug-resistant bacteria, mosquito-borne illnesses, and cardiovascular blood clotting disorders, paving the way for safer healthcare and environmental interventions.
The described methods could enable biotechnology and pharmaceutical developers to formulate biocompatible antimicrobial treatments, vector control larvicides, and cardiovascular therapies. Potential users include healthcare developers and disease control programmes. Because the source material evaluates research-level biomedical activities and general trends, the technology sits at an early stage of development, requiring substantial validation before reaching commercial production.
AI-generated from the published abstract. Always read the original work before citing.
The synthesis of metallic nanoparticles (MeNPs) through green approach has continued to court the interests of scientists from diverse background due to numerous beneficial reasons. The process is eco-friendly, devoid of the use of hazardous chemicals and procedures in the synthesis, which promotes their biocompatibility and low toxicity; it is economical, rapid, cost-effective, and can be accomplished under benign conditions. The abundance of several biomolecules in biological entities that can concomitantly serve as both reduction and capping agents has also fueled the growing trends in one-pot synthesis of MeNPs. Amongst the MeNPs, silver (Ag), gold (Au), and their bimetallic alloy (Ag–AuNPs) have been vividly studied owing to their novel optical, physical, chemical, photothermal, catalytic, and electrical attributes for multiple applications. Some of the important usefulness of these nanoparticles is in their deployment as antimicrobial, larvicidal, antioxidant, anticoagulant, and thrombolytic agents. These biomedical applications are envisaged to combat myriads of problems facing mankind, particularly the antimicrobial resistance phenomena, control of vector-borne diseases, deleterious activities of free radical species, and control/management of 4 blood coagulation disorders. It is evidently clear that properties exhibited by nanoparticles aptly positioned them to be used as vital tools in the development of new generation of nanomedicals. Therefore, this review presents the contributions of green synthesized Ag, Au, and Ag–AuNPs for biomedical applications with due diligence to antimicrobial, larvicidal, antioxidant, anticoagulant, and thrombolytic activities. Until now, there is no review that summarizes the biomedical applications of Ag, Au, and Ag–AuNPs as a compendium. The review underscores the importance of these particles in the emerging disciplines of nano- and biomedicine.
This page summarises published work. The authoritative version sits with the publisher.
DOI: 10.1201/9780429425660-1
Is something wrong with this record? Report it or request removal.
Discussion
Have you built on this work, tried to replicate it, or seen it applied in practice? Share what you know. Verified researchers and MARATTO™ domain experts can open a discussion, and any member can reply. Contributions are reviewed before they appear.
No discussion yet. Open the first thread.
New to MARATTO™? Create a free account.
