article · Journal of Pathology Research Reviews & Reports
We report a rare case of a giant vascular eccrine spiradenoma arising in the thigh of a 40-year-old man. The lesion measured 4 cm, was clinically painful, and was evaluated radiologically and histopathologically. The tumour showed the classical biphasic cellular architecture of spiradenoma with prominent vascularized stroma. Immunohistochemistry demonstrated diffuse positivity for pancytokeratin AE1/AE3, strong SMA positivity, and complete negativity for C34. Complete excision resulted in uneventful recovery with no recurrence after 12 months.
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DOI: 10.47363/jpr/2026(8)189
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