review · Plants
Plants within the genus Amorphophallus, belonging to the Araceae family, have a long history of use in traditional systems such as Ayurveda and Unani. These widely distributed plants contain a diverse array of bioactive compounds, particularly polyphenols, as well as alkaloids, steroids, tannins, proteins, fats, and carbohydrates. These constituents underpin a broad spectrum of documented pharmacological properties, including analgesic, anti-inflammatory, antioxidant, anticancer, antibacterial, neuroprotective, and hepatoprotective activities. They also demonstrate potential in regulating blood glucose, mitigating obesity, and addressing gastrointestinal disturbances. Furthermore, traditional applications target conditions such as acute rheumatism, tumours, lung swelling, asthma, vomiting, and abdominal pain. Amorphophallus species have consequently been incorporated into various herbal formulations and pharmaceutical products, alongside documented considerations regarding their toxicological profiles.
Traditional botanical medicines offer a rich starting point for developing modern therapeutics. By collating the chemical makeup, traditional applications, and pharmacological actions of Amorphophallus species, this work highlights how naturally occurring compounds could address common health challenges, ranging from chronic inflammation and metabolic conditions to microbial infections and cancer.
The findings are relevant to herbal product manufacturers and pharmaceutical developers seeking bioactive ingredients for anti-inflammatory, metabolic, or antimicrobial products. Amorphophallus species have already seen adoption in herbal formulations and pharmaceutical applications, indicating active use, though the review nature of the abstract means specific candidate molecules remain at an exploratory to early formulation stage.
AI-generated from the published abstract. Always read the original work before citing.
The genus Amorphophallus belongs to the family Araceae. Plants belonging to this genus are available worldwide and have been used in traditional medicines since ancient times, mainly in Ayurveda and Unani medical practices. Amorphophallus species are an abundant source of polyphenolic compounds; these are accountable for their pharmacological properties, such as their analgesic, neuroprotective, hepatoprotective, anti-inflammatory, anticonvulsant, antibacterial, antioxidant, anticancer, antiobesity, and immunomodulatory effects, as well as their ability to prevent gastrointestinal disturbance and reduce blood glucose. Moreover, Amorphophallus species contain numerous other classes of chemical compounds, such as alkaloids, steroids, fats and fixed oils, tannins, proteins, and carbohydrates, each of which contributes to the pharmacological effects for the treatment of acute rheumatism, tumors, lung swelling, asthma, vomiting, abdominal pain, and so on. Additionally, Amorphophallus species have been employed in numerous herbal formulations and pharmaceutical applications. There has been no extensive review conducted on the Amorphophallus genus as of yet, despite the fact that several experimental studies are being published regularly discussing these plants’ pharmacological properties. So, this review discusses in detail the pharmacological properties of Amorphophallus species. We also discuss phytochemical constituents in the Amorphophallus species and their ethnomedicinal uses and toxicological profiles.
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DOI: 10.3390/plants12233945
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