article · medRxiv

Genome admixture analysis of 1,030 Ugandan infants with neonatal sepsis and hydrocephalus demonstrates geographical stratification of population disease risk

Mercedeh Movassagh
Emmanuel Wegoye
Ronald Mulondo
John Mugamba
Jasmine Smith
Moses Ochora
James R. Broach
Claudio Fronterrè
Edith Mbabazi-Kabachelor
Peter Ssenyonga
Kathy Burgoine
Jessica E. Ericson
Elias Kumbakumba
Mallory Peterson
Christine Hehnly
Joseph N. Paulson
Davis Natukwatsa
Justin Onen
Lijun Zhang
Lucinda Newbury
Andrew J. Whalen
Enrique Mondragon Estrada
Ludinca Newbury
Sarah Morton
Peter Olupot-Olupot
Misaki Sasanami
Steven J. Schiff

2026Open accessMbarara University of Science and Technology

Abstract

This study underscores the importance of genetic factors in disease manifestation at the population level, and a role for such precision public health approaches in complex neonatal disorders in African populations.

Research topics

Infectious Encephalopathies and Encephalitis
Bacterial Infections and Vaccines
Fetal and Pediatric Neurological Disorders

Sustainable Development Goals

3Good Health and Well-being

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DOI: 10.64898/2026.03.16.26348489

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