article · Alzheimer s & Dementia
These findings nominate PHLPP1 as a shared locus for both AD and stroke in individuals of African ancestry. Notably, a genome-wide significant signal in this locus was identified in an admixture mapping study of African Americans (Rajabli et al., 2023). Identification of shared molecular mechanisms between AD and CVD in different populations is useful for understanding the relationship between these two processes in all people.
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DOI: 10.1002/alz70855_107411
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