review · Frontiers in Immunology
This review explores garlic's extensive health benefits, recognising it as a potent disease-preventive food. Garlic, a common spice, is rich in bioactive compounds such as allicin, ajoene, polysaccharides, and saponins. These components have been studied for their diverse therapeutic properties, including anticancer, anti-diabetic, anti-inflammatory, antioxidant, antimicrobial, immune-boosting, and cardioprotective effects. The research discusses the specific bioactive substances found in garlic, their biological functions, and the mechanisms through which they contribute to disease prevention and therapy. This comprehensive overview highlights garlic's potential role in improving human health.
Understanding garlic's bioactive compounds and their health benefits is crucial for promoting natural approaches to disease prevention and treatment. This knowledge can inform dietary recommendations and inspire further research into plant-based therapies, potentially leading to new ways to improve human health and well-being.
The abstract indicates that garlic's bioactive compounds have therapeutic applications and may play a role in drug development against various human diseases. This suggests potential for early-stage research into new pharmaceutical or nutraceutical products, targeting conditions like cancer, diabetes, and cardiovascular issues. The end-users could be pharmaceutical companies or health product manufacturers.
AI-generated from the published abstract. Always read the original work before citing.
Garlic (<i>Allium sativum</i> L.) is a widely abundant spice, known for its aroma and pungent flavor. It contains several bioactive compounds and offers a wide range of health benefits to humans, including those pertaining to nutrition, physiology, and medicine. Therefore, garlic is considered as one of the most effective disease-preventive diets. Many <i>in vitro</i> and <i>in vivo</i> studies have reported the sulfur-containing compounds, allicin and ajoene, for their effective anticancer, anti-diabetic, anti-inflammatory, antioxidant, antimicrobial, immune-boosting, and cardioprotective properties. As a rich natural source of bioactive compounds, including polysaccharides, saponins, tannins, linalool, geraniol, phellandrene, β-phellandrene, ajoene, alliin, S-allyl-mercapto cysteine, and β-phellandrene, garlic has many therapeutic applications and may play a role in drug development against various human diseases. In the current review, garlic and its major bioactive components along with their biological function and mechanisms of action for their role in disease prevention and therapy are discussed.
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DOI: 10.3389/fimmu.2024.1277074
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