article · Food, Nutrition and Health.
Fluted pumpkin, known scientifically as Telfairia occidentalis, serves as a rich source of nutrients and bioactive compounds across its leaves, seeds, fruits, and whole plant structure. These plant parts supply essential proteins, amino acids, vitamins, minerals, carbohydrates, fats, and fatty acids alongside valuable phytochemicals. Evidence shows that the plant exhibits diverse therapeutic properties, including neuroprotective, hepatoprotective, antioxidant, anti-inflammatory, antimicrobial, and anti-cancer actions. It also demonstrates potential in managing conditions through anti-ulcer, pro-reproduction, antiplasmodial, antinociceptive, and anti-hyperlipidemic mechanisms. Together, these functional and healing attributes make fluted pumpkin a significant botanical resource for disease prevention and health management. Its broad nutritional and medicinal profile supports multiple uses ranging from everyday human nutrition and food production to pharmaceutical formulations and dietary supplements.
Demand is growing globally for plant-based sources of nutrition and healing compounds that can both nourish populations and assist in disease management. Because fluted pumpkin contains rich concentrations of vital nutrients and diverse medicinal compounds, it offers substantial promise for public health interventions, nutritional therapies, and preventative medicine aimed at managing chronic and infectious health conditions.
The identified properties support potential commercial applications in food production, dietary supplements, and pharmaceutical formulations of therapeutics and nutraceuticals. Intended users include food manufacturers, clinical nutritionists, and pharmaceutical developers. Because the findings are drawn from a broad review of existing studies rather than specific product testing, the research represents an early-stage evidence base that requires formulation, safety validation, and applied clinical testing before reaching real-world market use.
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Abstract With the increasing search for existing and emerging natural sources of foods, nutrients and bioactive compounds with functional, nutraceutical, healing and medicinal functions, this study aims at evaluating the roles of Telfairia occidentalis Hook. f. in helping to meet this growing demand. This study reviewed recent studies on the nutritional, phytochemical, therapeutic, medicinal, nutraceutical, functional, and healing properties of Telfairia occidentalis and its seeds, leaves, fruits, and whole plant. Their roles in the treatment/management of many diseases, such as their neuro-protective, hepatoprotective, antioxidants, anti-ulcer, pro-reproduction, anti-inflammatory, antiplasmodial, anti-cancer, antimicrobial, antinociceptive, anti-hyperlipidemic, and pharmaceutical properties. Telfairia occidentalis and its seeds, leaves and fruits are excellent sources of vitamins, protein, minerals, essential amino acids, fats and fatty acids, carbohydrates, and important phytochemicals, all of which play important roles in health and disease prevention/treatment. These interesting properties of Telfairia occidentalis can be adequately explored for important applications in nutrition and dietetics, medicine, pharmacy, food production, formulation of dietary supplements, and development of therapeutics and nutraceuticals. Graphical Abstract Potential health effects of fluted pumpkin include neuro-protective, hepatoprotective, antioxidants, anti-ulcer, pro-reproduction, anti-inflammatory, antiplasmodial, anti-cancer, antimicrobial, antinociceptive, anti-hyperlipidemic, and pharmaceutical properties
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DOI: 10.1007/s44403-026-00063-2
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