article · Journal of drug targeting
studies revealed the downregulation of MMP9, TNFα, and NF-κB, accompanied by increased SOD and CAT levels, indicating superior anti-ageing, anti-inflammatory, and antioxidant effects compared to FIS suspension. FIS-AP-HYA-LIMOs decreased JNK expression, preserved the integrity of skin layers, and reduced collagen degradation. This is the first report on FIS-loaded limosomes, modified with AP and HYA to synergistically prevent UVB-induced photoaging.
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DOI: 10.1080/1061186x.2025.2573053
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