Exploring the Enhanced Oxidation Potential through Green Synthesis of Ofloxacin–Silver Complex: Investigating Silver and Ofloxacin Interaction at Varied Concentrations

Abstract

The purpose for this work is to synthesize ofloxacin–Silver(I) complex with the highest oxidation potential in liquid state with green methodology. Initially, we investigated the complexation of the OFL ligand with silver ions using UV-visible spectrophotometry, differential pulse wave voltammetry, and electrochemical impedance spectroscopy. The UV-visible results indicated the interaction between OFL and Ag + through a complexation reaction. Notably, the peak corresponding to OFL oxidation at 0.98 V showed a significant increase in the presence of silver, leading to an oxidation potential shift towards positive values attributed to the bond formation between the OFL and Ag + . In terms of structural characterization, various spectroscopic analyses were employed, including Fourier transform infrared spectroscopy (FTIR), X-ray diffraction, and scanning electron microscopy. The OFL–Ag + complex formation was confirmed by the appearance of two distinct sharp bands at 547 and 950 cm −1 in the FTIR spectra. The average particle diameter of the OFL–Ag + complex was determined to be 187.5 nm. This complex, synthesized as a brown solid powder soluble in water, exhibited the highest oxidation potential of 1.32 V. Hence, it holds promise for potential application in antibacterial activity.