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article · E3S Web of Conferences

Evaluation of the antispasmodic and antioxidant activities of an alkaloid extracted from <i>Pancratium foetidum</i> Pom. (Moroccan Endemic Amaryllidaceae)

2025Open accessMohamed I University

Abstract

Lycorine is a natural alkaloid extracted from the Amaryllidaceae plant family. It has been reported to exhibit a wide range of physiological effects, including the potential effect against cancer. The antispasmodic activity was investigated in vitro using rabbit intestine, and the antioxidant activity was evaluated by DPPH assay. The results indicated that lycorine has an irreversible relaxant property on the isolated rabbit jejunum. Whereas, it did not show a significant antioxidant activity toward the DPPH free radical in comparison with ascorbic acid.

Research topics

  • Chemical synthesis and alkaloids
  • Alkaloids: synthesis and pharmacology
  • Psychedelics and Drug Studies

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DOI: 10.1051/e3sconf/202563201007

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