article · Future Medicinal Chemistry

Evaluation of new 5-benzylidenethiazolidin-2,4-dione derivatives linked to nitric oxide donor oxime moiety as VEGFR-2 inhibitors and apoptosis inducers: design, synthesis, anti-proliferative assessment and <i>in silico</i> studies

Abeer M. Abd El-Hameed
Wael A. A. Fadaly
Taha H. Zidan
Naglaa M. Ahmed
May El-Manawaty
Fatma Magdy

2026Helwan University

In plain language

The abstract on record is too brief for a reliable plain-language summary, so none has been generated.

Abstract

The present work flags the approach for advanced expansion of powerful nitric oxide donor offshoots as VEGFR-2 inhibitors.

Research topics

Angiogenesis and VEGF in Cancer
Synthesis and biological activity
Chemotherapy-induced cardiotoxicity and mitigation

Read the original research

This page summarises published work. The authoritative version sits with the publisher.

View on publisher site Record on OpenAlex

DOI: 10.1080/17568919.2026.2642678

Is something wrong with this record? Report it or request removal.

Discussion

Discuss this research

Have you built on this work, tried to replicate it, or seen it applied in practice? Share what you know. Verified researchers and MARATTO™ domain experts can open a discussion, and any member can reply. Contributions are reviewed before they appear.

No discussion yet. Open the first thread.

New to MARATTO™? Create a free account.