Evaluation of Cognition in Mild Cognitive Impairment and Cognitively Intact Group: A Follow Up Study

Abstract

Abstract Introduction Assessment of cognition in elderly is essential. Mild cognitive impairment (that also known as isolated memory impairment or incipient dementia) is a brain function syndrome involving both the evolution and onset of cognitive impairments that is beyond what would be expected based on an individual's age education, but is not significant enough to interfere with their daily activities. Objective To evaluate whether there is change of cognition in mild cognitive impairment and control group over a period of 6 months. Methods A case control study was conducted on total160 elderly patients (80 person in MCI group and 80 persons in cognitively intact group) that were recruited from ASU hospitals (inpatients and outpatients). All patients underwent comprehensive geriatric assessment and follow up after 6 months by cognitive function tests. Results Cognitive assessment at first visit and follow up visit in MCI group regarding MOCA test executive (P = 0.021) and orientation (P = 0.035) were, in case of MMSE attention (P = 0.023), recall (P = 0.034) and language (P = 0.020) were statically significant. Also regarding CDR, orientation (P = 0.005), community affairs (P = 0.028) and home and hobbies (P = 0.042) were statistically significant. While the cognitive assessment of cognitively intact group, that there was no statistical significant regarding MMSE, CDR, MOCA at first visit and follow up visit. Conclusion Different cognitive assessment items were affected in MCI group over a 6 month period.