Evaluating the efficacy and clinical outcomes of minimally invasive laser interstitial thermal therapy in the treatment of recurrent glioblastoma multiforme: meta-analysis protocol

Abstract

Abstract Laser interstitial thermal therapy (LITT) is a neurosurgical technique that has become increasingly popular in recent years due to its minimally invasive nature and ability to reduce the size of brain tumors. Advances in technology, such as magnetic resonance imaging thermometry and better laser probe design, have made LITT procedures more feasible and safe. Many studies have been conducted on using LITT to treat various conditions like tumors and epilepsy, but the specific uses for LITT are still evolving. In this article, we explain the basic principles of LITT, the process of performing the procedure, and both established and emerging applications for it. The effectiveness of LITT in treating recurrent glioblastoma (rGBM) is not yet established. This study aimed to systematically review and analyze existing literature to determine the outcomes of patients with rGBM who undergo LITT.