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article · PLoS neglected tropical diseases

Epidemiology and treatment outcomes of recurrent tuberculosis in Tanzania from 2018 to 2021 using the National TB dataset

20246 citationsOpen accessUniversity of the Witwatersrand

Abstract

TB recurrence in Tanzania accounts for 2% of all TB cases, and it is associated with poor treatment outcomes. Unfavourable treatment outcomes were recorded in 10% of patients with recurrent TB. Poor TB treatment outcome was associated with HIV-positive status, facility-based DOT, bacteriologically confirmed TB and receiving treatment at the hospital level, differing among regions. We recommend post-treatment follow-up for patients with recurrent TB, especially those coinfected with HIV. We also propose close follow-up for patients treated at the hospital facility level and strengthening primary health facilities in TB detection and management to facilitate early treatment initiation.

Research topics

  • Tuberculosis Research and Epidemiology
  • Pneumocystis jirovecii pneumonia detection and treatment
  • HIV/AIDS Research and Interventions

Sustainable Development Goals

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DOI: 10.1371/journal.pntd.0011968

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