Electrodermal Activity Dysregulation and Compression Therapy in Patients with Lumbosacral Radiculopathy: A Narrative Review

Abstract

Background: lumbosacral radiculopathy is a painful disorder that starts in the buttocks and travels down the leg due to irritation or compression of the sciatic nerve. Condition is usually harmless and goes away on its own. Pain in the lower back that travels down one or both legs is a hallmark of this condition, as are neurological symptoms such as paresis, impaired sensation, or a lack of reflexes, all of which point to irritation of nerve roots or a malfunction in the nervous system. Humans exhibit Electrodermal activity (EDA), a trait that results in constant change in the skin's electrical properties. One another name for EDA is skin conductance (SC). According to EDA, the condition of the skin's sweat glands determines the skin's resistance and skin conductance condition changes. Purpose: This review aimed to explore the EDA dysregulation in patients with lumbosacral Radiculopathy and also to which extent the compression therapy in previous literature may have effect on it. Methods: By searching for papers published between 2000 and 2024 that were relevant, a thorough literature search was performed using PubMed, Cochrane Library, Web of Science, Scopus, and Google Scholar. Electrodermal activity (EDA), lumbar radiculopathy, and compression treatment(CT) were the search phrases employed. We only considered observational studies, systematic reviews, meta-analyses, and randomized controlled trials (RCTs) that were published in English. Results: Studies have linked compression treatment interventions to changes in autonomic nervous system activation, changes is the EDA activity which reflects better on the patients functional activity, and allow better patient engagement in rehabilitation programs. Conclusion: By addressing the neurological aspects of rehabilitation, compression treatment shows promise as an intervention for lumbosacral radiculopathy. Adding CT to interdisciplinary rehabilitation programs has the potential to boost patient engagement and quality of life improvement that enhance functional rehabilitation for those patients as supported by the previous data.